口腔癌基因體學

Overview

Retinoic acid and androgen receptors combine to achieve tissue specific control of human prostatic transglutaminase expression: a novel regulatory network with broader significance.

Targeting the FOXO1/KLF6 axis regulates EGFR signaling and treatment response.

Discussion I - EGFR

EGFR Kinase Promotes Acquisition of Stem Cell-Like Properties: A Potential Therapeutic Target in Head and Neck Squamous Cell Carcinoma Stem Cells.

TGF-b and NF-kB signal pathway cross-talk is mediated through TAK1 and SMAD7 in a subset of head and neck cancers.

Acquisition of EMT phenotype in the gefitinib-resistant cells of a head and neck squamous cell carcinoma cell line through Akt/GSK-3b/snail signalling pathway.

Discussion II - EMT

Metformin Prevents the Development of Oral Squamous Cell Carcinomas from Carcinogen-Induced Premalignant Lesions.

VHL-Regulated MiR-204 Suppresses Tumor Growth through Inhibition of LC3B-Mediated Autophagy in Renal Clear Cell Carcinoma.

miR-31 is a negative regulator of fibrogenesis and pulmonary fibrosis.

Discussion III - Micro RNA

Numb Regulates Glioma Stem Cell Fate And Growth by Altering EGFR and SCF Ubiquitin Ligase Activity.

Evidence for alteration of EZH2, BMI1, and KDM6A and epigenetic reprogramming in human papillomavirus type 16 E6/E7-expressing keratinocytes.

MicroRNA-21 Modulates the Levels of Reactive Oxygen Species Levels by Targeting SOD3 and TNF.

Discussion IV - Autophagy

Review

Final Examination