進階生物藥學專題討論

09/30(Wed) 施繼庭 Small-molecule MYC inhibitors suppress tumor growth and enhance immunotherapy Cancer Cell. 2019; 36: 483-497

10/07(Wed) Thi-Thu-Phuong Bui 彭裴氏 A MYC-GCN2-eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer Nature cell biology. 2019; 21:1413-1424

10/8 (Thur) Dr. Huang and Dr. Mu-Hsin Chang Thu-Huyen Hoang 黃玉玄 Synthetic lethality between VPS4A and VPS4B triggers an inflammatory response in colorectal cancer. Molecular Medicine. 2020.

10/14(Wed) Dr Une-Fang Ueng Xuan-Tung Ha 何春崧 Knockout of farnesoid X receptor aggravates process of diabetic cardiomyopathy

10/15 (Thur) Dr. Huang, Dr. Chia-Jen Liu, Dr. Young-Ji Shiao Thi-Quynh-Trang Dao 莊氏瓊桃 HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer’s disease Nature Communication. 2020; 11:2484

10/21(Wed) Thi-Hong-Hanh Le 黎虹涵 Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension

10/22 (Thur) Dr. Huang and Dr. Mu-Hsin Chang Tri-Vien Le 袁治黎 Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC

11/04(Wed) Midterm

11/18(Wed) Thuc-Anh Nguyen 阮淑英 USP7 inhibits Wnt/β-catenin signaling through promoting stabilization of Axin Nature communication. 2019; 10:4184.

11/25(Wed) Hien-Ly Doan 尹嫻璃 Antitumor immunity augments the therapeutic effects of p53 activation on acute myeloid leukemia Nature communication. 2019; 4869

11/26 (Thur) Dr. Huang and Dr. Chia-Jen Liu Huong Thi Nguyen NADPH production by the oxidative pentose-phosphate pathway supports folate metabolism Nature Metabolism. 2019; 1:404-415

12/02(Wed) Thi-My-Trieu Tran 趙氏媚陳 Anticancer effects of epigallocatechin-3-gallate nanoemulsion on lung cancer cells through the activation of AMP-activated protein kinase signaling pathway Nature. 2020; 10:5163

12/3 (Thur) Dr. Huang and Dr. Mu-Hsin Chang Trang Thi Huyen Nguyen Nrf2 Activation Promotes Lung Cancer Metastasis by Inhibiting the Degradation of Bach1 Cell. 2019; 178(2): 316-329.e18

12/10 (Thur) Dr. Huang and Dr. Chia-Jen Liu My Nu Huyen Nguyen Pharmacokinetic tuning of protein–antigen fusions enhances the immunogenicity of T-cell vaccines Nature Biomedical engineering. 2020; 4: 636-648

12/16(Wed) 田婷怡 T cells with dysfunctional mitochondria induce multimorbidity and premature senescence. Science,2020 June 19; 368:1371–1376.

12/23(Wed) 賴信宏 FOXO3-Engineered Human ESC-Derived Vascular Cells Promote Vascular Protection and Regeneration. Cell Stem Cell. 2019 Mar;24(3):447-461.e8. DOI: 10.1016/j.stem.2018.12.002.

12/30(Wed) Final -

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