實驗動物疾病學
Diseases in Laboratory Animals
| 節 | 週四 |
|---|---|
5 13:20–14:10 | 實驗動物疾病學 BI301（博愛） 3 節連堂 |
6 14:20–15:10 | |
7 15:30–16:20 |
* 根據陽明交大上課時間表所列
本課程為生物科技學院「實驗動物模式模組化課程」之一,將介紹實驗動物常見的健康異常與疾病,其在動物實驗過程中對動物的影響,以及對實驗結果判讀可能造成的干擾。首先將導入引發疾病發生的基本概念,而在嘗試辦識疾病之前必須了解動物在健康狀況下、所呈現正常行為學、解剖學、及組織學等方面的知識。因此本課程將以最常見的實驗動物,即小鼠及大鼠,和同學最熟悉的物種,即人類,在解剖學及組織學的層面進行比較,點出其相似及不同之處,以建立對正常動物應有的形態學相關知識。隨後簡介和疾病發生息息相關的微生物學與寄生蟲學,辦識疾病的病理學,介紹實驗囓齒類、兔、犬、貓、非人類靈長類等動物常見的健康異常與疾病,還有這些疾病的診斷、治療、預防方法等,以及實驗大、小鼠正規病理解剖的流程。此外,課程中也將特別強調實驗動物有關的人畜共通傳染病,以使同學在專注動物實驗的同時,也具備相關知識以保護自身免於受到這些傳染性疾病的侵害。
不限,歡迎對實驗動物解剖、組織、病理、及疾病有興趣的同學選修。
無備註
教科書: 1. http://www.sciencedirect.com/science/book/9780123813619 2. http://www.sciencedirect.com/science/article/pii/S0940299304701487 3. http://www.sciencedirect.com/science/article/pii/S0940299304701876 4. http://www.sciencedirect.com/science/article/pii/S0940299304701888
期中報告(15%)、期中考(25%)、期末報告(25%)、期末考(25%)、課程參與及出席(10%)
Human vs. Mouse
1. Gross Anatomy 2. Physiology
- 講授：
- 3
General Concepts of Disease
1. Basic Concepts of Pathology 2. Basic Concepts of Microbiology 3. Basic Concepts of Parasitology
- 講授：
- 3
Histology
1. Basic Concepts of Histology 2. Major Tissue Types in Histology 3. Necropsy and Organ Sampling in Rat and Mice
- 講授：
- 9
Comparative Anatomy and Histology of Human and Mouse
1. Cardiovascular and Respiratory Systems 2. Skeletal and Endocrine Systems 3. Digestive System 4. Urinary and Male Reproductive Systems 5. Female Reproductive, Lymphoid, Hematopoietic, and Skin Systems 6. Nervous System and Special Sense Organs
- 講授：
- 18
Common Health Disorders and Diseases of Laboratory Animals
1. Mouse and Rat 2. Rabbit 3. Non-human Primates
- 講授：
- 9
Student’s Presentation
- 其他：
- 6
| 週次 | 主題 |
|---|---|
| 第 1 週 | Course Introduction 2/17 |
| 第 2 週 | Laboratory Animals and General Concepts for Disease 2/24 |
| 第 3 週 | Human vs. Mouse: Gross Anatomy and Physiology 3/3 |
| 第 4 週 | Basic Concepts for Histology 3/10 |
| 第 5 週 | Major Tissue Types in Histology: Epithelial, Connective, Nervous, and Muscular Tissues 3/17 |
| 第 6 週 | Comparative Anatomy and Histology of Human and Mouse: Skeletal and Endocrine Systems 3/24 |
| 第 7 週 | Comparative Anatomy and Histology of Human and Mouse: Nervous System Student’s Presentation: Techniques and Special Staining Used in Diagnosis of Diseases – 1 3/31 |
| 第 8 週 | Mid-term Examination Student’s Presentation: Techniques and Special Staining Used in Diagnosis of Diseases – 2 4/7 |
| 第 9 週 | Comparative Anatomy and Histology of Human and Mouse: Cardiovascular and Respiratory Systems 4/14 |
| 第 10 週 | Comparative Anatomy and Histology of Human and Mouse: Digestive System 4/21 |
| 第 11 週 | Comparative Anatomy and Histology of Human and Mouse: Urinary and Male Reproductive Systems 4/28 |
| 第 12 週 | Comparative Anatomy and Histology of Human and Mouse: Female Reproductive, Lymphoid, Hematopoietic, and Skin Systems 5/5 |
| 第 13 週 | Common Health Disorders and Diseases of Lab Animals – 1 5/12 |
| 第 14 週 | Common Health Disorders and Diseases of Lab Animals – 2 5/19 |
| 第 15 週 | Student’s Presentation: Laboratory Animal-related Zoonosis – 1 5/26 |
| 第 16 週 | Final Examination Student's Presentation: Laboratory Animal-related Zoonoses – 2 6/2 |
1. Comparative Anatomy and Histology - A Mouse and Human Atlas. Elsevier Inc., USA, 2012. 2. Revised guides for organ sampling and trimming in rats and mice – Part I, Exp. Toxic Pathol., 55: 91-106, 2003. 3. Revised guides for organ sampling and trimming in rats and mice – Part II, Exp. Toxic Pathol., 55: 413-431, 2004. 4. Revised guides for organ sampling and trimming in rats and mice – Part III, Exp. Toxic Pathol., 55: 433-449, 2004.
- 地點
- 賢齊館518室
- 時間
- 星期四下午16:30-17:30
- 聯絡方式
- #56995 mairt@nycu.edu.tw