臨床研究設計
Designing Clinical Research
| 節 | 週四 |
|---|---|
5 13:20–14:10 | 臨床研究設計 YT204（陽明） 2 節連堂 |
6 14:20–15:10 |
* 根據陽明交大上課時間表所列
課程內容涵蓋: 1) 臨床研究重要組成。2) 臨床研究結果推論過程中,偏差與干擾因子之影響。3) 研究問題提出與研究對象選擇。4) 研究變項測量之效度與信度。5) 常見臨床研究設計與選擇考量。6) 樣本數計算。7) 如何精進臨床研究結果正確性。There are several major areas which will be emphasized: 1) what a clinical research is composed of and how it is operated; 2) how to come up with research questions & how to select study subjects; 3) what validity & reliability are, and how they affect a study; 4) what different study designs are commonly used in clinical researches and; 5) how study designs can be employed in clinical pharmacy researches.
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課程整體目標在培養學生具備臨床研究設計重要概念與執行臨床研究基本能力。Develop students to have basic concept and abilities in designing clinical researches
30% 課堂討論與表現。35% 期中考。35% 期末考。30% class participation; 35% midterm exam; 35% final exam
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| 週次 | 主題 |
|---|---|
| 第 1 週 | Course introduction & overview of study design 2022/02/17 |
| 第 2 週 | The anatomy and physiology of clinical research 2022/02/24 |
| 第 3 週 | Conceiving the research questions 2022/03/03 |
| 第 4 週 | Choosing the study subjects 2022/03/10 |
| 第 5 週 | Threats to internal validity 2022/03/17 |
| 第 6 週 | Case discussion (I) 2022/03/24 |
| 第 7 週 | Planning the measurements: Precision & Accuracy 2022/03/31 |
| 第 8 週 | Introduction of study design & Designing a cohort study 2022/04/07 |
| 第 9 週 | Mid-term exam 2022/04/14 |
| 第 10 週 | Designing cross-sectional and case-control studies 2022/04/21 |
| 第 11 週 | Enhancing causal inferences in observational studies 2022/04/28 |
| 第 12 週 | Case discussion (II) 2022/05/05 |
| 第 13 週 | Designing a randomized controlled trial 2022/05/12 |
| 第 14 週 | Estimate sample size 2022/05/19 |
| 第 15 週 | Case discussion (III) 2022/05/26 |
| 第 16 週 | Final exam 2022/06/02 |
| 第 17 週 | 2022/06/09 |
| 第 18 週 | 2022/06/16 |
Hulley, S. B., Cummings, S. R., Browner, W. S., Grady D.G. & Newman, T. B. (2013). Designing clinical research (4th ed.). New York: Lippincott Williams & Wikins.
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