醫藥化學(一)
Medicinal Chemistry (1)
| 節 | 週二 |
|---|---|
5 13:20–14:10 | 醫藥化學(一) YC101（陽明） 2 節連堂 |
6 14:20–15:10 |
* 根據陽明交大上課時間表所列
Outline: Medicinal chemistry is the basic knowledge essential for modern drug discovery and development. For students (especially the Ph.D. students) of our Institute, this course is the advance of Biopharmaceutical Sciences and Trends in New Drug Development which will be taught in two semesters and the contents are primarily based on the arrangement of the main textbook (i.e., Foye’s Principles of Medicinal Chemistry). Topics including the relationship between functional groups and pharmacological activity of various drugs, drug design via molecular modeling, receptors and drug action, drug design through enzyme inhibition, pharmaceutical biotechnology, and bioactive natural products etc will be taught during the first half of the first semester. And topics such as physiochemical and biopharmaceutical properties of drug substances & pharmacokinetics, drug metabolism, drugs affecting cholinergic and adrenergic neurotransmission, amino acid neurotransmitters in the CNS, hypnotics and sedatives, serotonin receptors and antidepressants, and anesthetics will be taught in the second half of this semester.
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_Close book exam
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| 週次 | 主題 |
|---|---|
| 第 1 週 | 09/13(二) Introduction of medicinal chemistry 2 Dr. Yeu Su 09/13(二) |
| 第 2 週 | 09/20(二) Drug design and relationship of functional groups to pharmacological activity 2 Dr. Chung-Wai Shiau 09/20(二) |
| 第 3 週 | 09/27(二) Molecular modeling and drug design 2 Dr. Chung-Wai Shiau 09/27(二) |
| 第 4 週 | 10/04(二) Receptors as targets for drug discovery 2 Dr. Yeu Su 10/04(二) |
| 第 5 週 | 10/11(二) Pharmaceutical biotechnology 2 Dr. Yeu Su 10/11(二) |
| 第 6 週 | 10/18(二) Bioactive natural products 2 Dr. Jih-Jung Chen 10/18(二) |
| 第 7 週 | 10/25(二) Drug design through enzyme inhibition 2 Dr. Chung-Wai Shiau 10/25(二) |
| 第 8 週 | 11/01(二) Mid-term examination 2 Dr. Yeu Su 11/01(二) |
| 第 9 週 | 11/08(二) Drugs affecting cholinergic neurotransmission 2 Dr. Yeu Su 11/08(二) |
| 第 10 週 | 11/15(二) Drugs affecting adrenergic neurotransmission 2 Dr. Tsiu-Ting Ching 11/15(二) |
| 第 11 週 | 11/22(二) Physiochemical and biopharmaceutical properties of drug substances & pharmacokinetics 2 Dr. Teh-Min Hu 11/22(二) |
| 第 12 週 | 11/29(二) Drug metabolism 2 Dr. Yune-Fang Ueng 11/29(二) |
| 第 13 週 | 12/06(二) Basic and clinical aspects of Parkinson’s disease 2 Dr. Maan-Yuh Lin 12/06(二) |
| 第 14 週 | 12/13(二) Serotonin receptors and drugs affecting serotonergic neurotransmission 2 Dr. Tung-Ping Sun 12/13(二) |
| 第 15 週 | 12/20(二) Anesthetics 2 Dr. Yeu Su 12/20(二) |
| 第 16 週 | 12/27(二) Final examination 2 Dr. Yeu Su 12/27(二) |
| 第 17 週 | 01/03(二) Make-up class 2 Dr. Yeu Su 01/03(二) |
| 第 18 週 | 01/10(二) Make-up class 2 Dr. Yeu Su 01/10(二) |
References: Foye’s Principles of Medicinal Chemistry (8th edition) 2019 Edited by T.L. Lemke and D.A.Williams Publisher: Lipincott Williams & Wilkins
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