生物序列分析與高通量技術
Biological Sequence Analysis and High Throughput Technologies
| 節 | 週一 |
|---|---|
5 13:20–14:10 | 生物序列分析與高通量技術 BI301（博愛） 3 節連堂 |
6 14:20–15:10 | |
7 15:30–16:20 |
* 根據陽明交大上課時間表所列
This class introduces the history of sequencing technologies in terms of their thermodynamic and chemical reaction principles and the applications of Next Generation Sequencing (NGS) with examples of the basic analysis. Several NGS strategies are covered, including whole genome sequencing, whole exome sequencing, RNA sequencing and metagenomics. Given that most of the NGS tools are Linux based, a taste of the Linux system will be given to students in the beginning of the course. Linux system and the scripting programming language R will be used in most of the examples.
基本分子生物學概念 (basic knowledge in molecular biological)
無備註
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Midterm (10%); Home work (40%); (in class) discussion & paper reading (20%); final project (oral presentation) (30%)
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| 週次 | 主題 |
|---|---|
| 第 1 週 | Introduction 2024-02-19(一) |
| 第 2 週 | Introduction of Next Generation Sequencing (NGS) 2024-02-26(一) |
| 第 3 週 | Introduction of Linux (I) 2024-03-04(一) |
| 第 4 週 | Introduction of Linux (II) 2024-03-11(一) |
| 第 5 週 | Whole genome sequencing 2024-03-18(一) |
| 第 6 週 | Target sequencing (Whole exome sequencing & disease panels) 2024-03-25(一) |
| 第 7 週 | Transcriptome profiling & functional analysis (I) 2024-04-01(一) |
| 第 8 週 | Midterm project 2024-04-08(一) |
| 第 9 週 | Transcriptome profiling & functional analysis (II) 2024-04-15(一) |
| 第 10 週 | Transcriptome profiling & functional analysis (III) 2024-04-22(一) |
| 第 11 週 | Introduction of R (I) 2024-04-29(一) |
| 第 12 週 | Introduction of R (II) 2024-05-06(一) |
| 第 13 週 | Small RNA Sequencing 2024-05-13(一) |
| 第 14 週 | Bacterial genome assembly (NGS & 3rd generation sequencing) 2024-05-20(一) |
| 第 15 週 | Final project rehearsal (I) 2024-05-27(一) |
| 第 16 週 | Final project rehearsal (I) 2024-06-03(一) |
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- 地點
- BIO-ICT building R420
- 時間
- Fri 9:00-10:00
- 聯絡方式
- 03-5712121 ext. 59734