蛋白質物理生化學
Physical Biochemistry of Protein
| 節 | 週一 |
|---|---|
5 13:20–14:10 | 蛋白質物理生化學 BI308（博愛） 3 節連堂 |
6 14:20–15:10 | |
7 15:30–16:20 |
* 根據陽明交大上課時間表所列
使學生對蛋白質之生物物理化學機制有所認知與徹底瞭解
建議需具備普通物理與普通化學以上之修課經驗與能力
無備註
教師未提供此項資料
出席率: 20% 作業部份：30% 期末報告: 50%
1. Introduction of protein 2. Elementary interactions in and around proteins 3. Secondary structure of polypeptide chains 4. Protein structures 5. Cooperation transitions in protein molecules 6. Prediction and design of protein structure. 7. Physical background of protein functions
同左
- 講授：
- 70%
- 示範：
- 10%
- 其他：
- 討論 20%
| 週次 | 主題 |
|---|---|
| 第 1 週 | Introduction of protein:Main functions of proteins 2026-02-23(一) 時數：[2026-02-23]張家靖(3.00) |
| 第 2 週 | Elementary interactions in and around proteinsa. Stereochemistry of L- amino acidsb. Covalent bonds and angles between themc. Vibration, rotation around the covalent bondsd. Van de Waals interaction 2026-03-02(一) 時數：[2026-03-02]張家靖(3.00) |
| 第 3 週 | Elementary interactions in and around proteinse. Influence of water environmentf. Hydrogen bonds and their electrostatic origing. Elements of thermodynamicsh. Water-accessible surface of proteini. Influence of aqueous environment on electrostatic interactions 2026-03-09(一) 時數：[2026-03-09]張家靖(3.00) |
| 第 4 週 | Secondary structure of polypeptide chainsa. Elementary of statistical mechanicsb. Temperature and probability of states with different energyc. The first order phase transitions 2026-03-16(一) 時數：[2026-03-16]張家靖(3.00) |
| 第 5 週 | Secondary structure of polypeptide chains d. The theory of reaction ratese. Zipper model of alpha-helicesf. beta-structure stability in waterg. Properties of amino acid side chains 2026-03-23(一) 時數：[2026-03-23]張家靖(3.00) |
| 第 6 週 | Protein structuresa. Fibrous proteins and their functionsb. Membrane proteins and their and their functions 2026-03-30(一) 時數：[2026-03-30]張家靖(3.00) |
| 第 7 週 | Protein structuresc. Globular proteins and their and their functionsd. Intrinsic disorder proteins and their functions 2026-04-06(一) 時數：[2026-04-06]張家靖(3.00) |
| 第 8 週 | Protein structurese. Classification of protein foldsf. Selection rule of protein structure 2026-04-13(一) 時數：[2026-04-13]張家靖(3.00) |
| 第 9 週 | Cooperation transitions in protein moleculesa. Cooperative transitionsb. Protein denaturation 2026-04-20(一) 時數：[2026-04-20]張家靖(3.00) |
| 第 10 週 | Cooperation transitions in protein moleculesc. Protein foldingd. Protein aggregation 2026-04-27(一) 時數：[2026-04-27]張家靖(3.00) |
| 第 11 週 | Prediction and design of protein structurea. Secondary structure prediction 2026-05-04(一) 時數：[2026-05-04]張家靖(3.00) |
| 第 12 週 | Prediction and design of protein structure b. Tertiary structure prediction 2026-05-11(一) 時數：[2026-05-11]張家靖(3.00) |
| 第 13 週 | Physical background of protein functionsa. Structure function relationship of proteins 2026-05-18(一) 時數：[2026-05-18]張家靖(3.00) |
| 第 14 週 | Physical background of protein functions b. Combination of elementary protein functions and flexibility of its structure 2026-05-25(一) 時數：[2026-05-25]張家靖(3.00) |
| 第 15 週 | Special topics report, presentation and discussion 2026-06-01(一) 時數：[2026-06-01]張家靖(3.00) |
| 第 16 週 | 期末考周 2026-06-08(一) 時數：[2026-06-08]張家靖(3.00) |
| 第 17 週 | 彈性授課周 2026-06-15(一) 時數：[2026-06-15]張家靖(3.00) |
| 第 18 週 | 彈性授課周 2026-06-22(一) 時數：[2026-06-22]張家靖(3.00) |
Protein physics: A course of Lectures. Authors: Alexei V Finkelstein and Oleg B Ptitsyn Academic Press 2002
- 地點
- 生科實驗二館203室
- 時間
- 每星期二早上9:00~12:00
- 聯絡方式
- ext 31633